Anti-seizure drug may guard against some cancers - NewsChannel5.com | Nashville News, Weather & Sports

Anti-seizure drug may guard against some cancers

Updated:
© iStockphoto.com / Thinkstock © iStockphoto.com / Thinkstock

MONDAY, March 24, 2014 (HealthDay News) -- A drug used to treat seizures may reduce the risk of head and neck cancers, a new study suggests.

Valproic acid (Depakote) is prescribed to prevent seizures and also to control mood, but it is also being investigated for cancer prevention because it inhibits genetic changes that can lead to cancer.

The new study included nearly 440,000 U.S. veterans, including about 27,000 who were taking valproic acid for bipolar disorder, post-traumatic stress disorder (PTSD), migraines and seizures. Overall, veterans who took the drug for at least one year were 34 percent less likely to develop head and neck cancers than those who didn't take the drug, the investigators found.

The risk appeared to be even lower in those who took it in higher doses or for longer periods of time, according to the study published online March 24 in the journal Cancer.

Veterans who took valproic acid did not have a reduced risk for lung, bladder, colon or prostate cancers, said team leader Dr. Johann Christoph Brandes, of the Atlanta Veterans Affairs Medical Center and Emory University in Atlanta, and colleagues.

"A 34 percent risk reduction for the development of head and neck cancer with [valproic acid] use could result in the prevention of up to approximately 16,000 new cases and 3,000 to 4,000 annual deaths in the U.S. alone," Brandes said in a journal news release.

"Head and neck cancer is an important global health crisis, and low cost and low toxicity prevention strategies like [valproic acid] use have a high potential impact on pain, suffering, costs, and [death] associated with this disease," he added.

Although the study found an association between valproic acid use and reduced risk of certain cancers, it did not prove cause-and-effect.

More information

The U.S. National Cancer Institute has more about head and neck cancers.

Copyright © 2014 HealthDay. All rights reserved.

  • Medical News HeadlinesMedical News HeadlinesMore>>

  • Drug To Prevent Alzheimer's

    Drug To Prevent Alzheimer's

    Tuesday, July 22 2014 5:15 PM EDT2014-07-22 21:15:05 GMT
    Everyone-- no matter if you are a man or woman, family history or not-- with a brain is at risk for Alzheimer’s disease. Age is the biggest risk factor and America is aging. Right now, dozens of research sites across the country are testing an experimental drug to see if it might prevent memory loss associated with this terrible disease.more>>
    Everyone-- no matter if you are a man or woman, family history or not-- with a brain is at risk for Alzheimer’s disease. Age is the biggest risk factor and America is aging. Right now, dozens of research sites across the country are testing an experimental drug to see if it might prevent memory loss associated with this terrible disease.more>>
  • Could Down Syndrome Be The Key To Alzheimer's?

    Could Down Syndrome Be The Key To Alzheimer's?

    Monday, July 21 2014 5:15 PM EDT2014-07-21 21:15:13 GMT
    More than five million Americans are living with Alzheimer’s. More than 400,000 of them also have Down syndrome. What does a condition seen at birth have in common with a disease typically diagnosed in the elderly? Quite a bit.more>>
    More than five million Americans are living with Alzheimer’s. More than 400,000 of them also have Down syndrome. What does a condition seen at birth have in common with a disease typically diagnosed in the elderly? Quite a bit.more>>
  • Extreme Workouts

    Extreme Workouts

    Friday, July 18 2014 6:04 PM EDT2014-07-18 22:04:23 GMT
    Workout routines have taken a tortuous turn. Running through mud and fighting in cages are just some of the latest extreme workouts, but one wrong move and you could be in trouble.more>>
    Workout routines have taken a tortuous turn. Running through mud and fighting in cages are just some of the latest extreme workouts, but one wrong move and you could be in trouble.more>>
  • Extreme Skin

    Extreme Skin

    Thursday, July 17 2014 5:15 PM EDT2014-07-17 21:15:05 GMT
    Last year, Americans underwent more than 11-million cosmetic procedures and spent nearly $12-billion on skin rejuvenation. Everyone wants their skin to look younger, healthier and better, but some are taking it to an extreme.more>>
    Last year, Americans underwent more than 11-million cosmetic procedures and spent nearly $12-billion on skin rejuvenation. Everyone wants their skin to look younger, healthier and better, but some are taking it to an extreme.more>>
  • Extreme Diets

    Extreme Diets

    Wednesday, July 16 2014 5:15 PM EDT2014-07-16 21:15:07 GMT
    Dieting is an American pastime. About 45-million of us diet each year, and we spend about $33-billion on weight-loss products. There are more ways to diet than ever and some are pretty extreme.more>>
    Dieting is an American pastime. About 45-million of us diet each year, and we spend about $33-billion on weight-loss products. There are more ways to diet than ever and some are pretty extreme.more>>
  • Frozen Lumpectomy For Prostate

    Frozen Lumpectomy For Prostate

    Tuesday, July 15 2014 5:15 PM EDT2014-07-15 21:15:08 GMT
    More than 230,000 men will be diagnosed with prostate cancer this year according to the American Cancer Society. In most cases, surgical removal of the gland is considered the gold standard of treatment, but results of a new study suggest a new treatment might benefit some patients.more>>
    More than 230,000 men will be diagnosed with prostate cancer this year according to the American Cancer Society. In most cases, surgical removal of the gland is considered the gold standard of treatment, but results of a new study suggest a new treatment might benefit some patients.more>>
  • Bariatric Surgery For Diabetes

    Bariatric Surgery For Diabetes

    Wednesday, July 9 2014 5:15 PM EDT2014-07-09 21:15:09 GMT
    Nearly 90 percent of people with type-two diabetes are obese and as more Americans gain weight, more will likely face a diabetes diagnosis. In fact, the American Diabetes Association predicts that one in three adults will have diabetes by the year 2050. For years, we’ve heard about weight loss surgery and its effect on diabetes. Now, a new study is showing how well the popular surgery is working to stop this serious disease.more>>
    Nearly 90 percent of people with type-two diabetes are obese and as more Americans gain weight, more will likely face a diabetes diagnosis. In fact, the American Diabetes Association predicts that one in three adults will have diabetes by the year 2050. For years, we’ve heard about weight loss surgery and its effect on diabetes. Now, a new study is showing how well the popular surgery is working to stop this serious disease.more>>
  • Ankle Replacement

    Ankle Replacement

    Tuesday, July 8 2014 5:15 PM EDT2014-07-08 21:15:10 GMT
    More than 50 million Americans suffer from some form of arthritis. Between 6 percent and 13 percent of them have ankle arthritis. These patients feel pain with every single step they take, but now ankle replacements are giving patients a new lease on life.more>>
    More than 50 million Americans suffer from some form of arthritis. Between 6 percent and 13 percent of them have ankle arthritis. These patients feel pain with every single step they take, but now ankle replacements are giving patients a new lease on life.more>>
  • 3D Knee

    3D Knee

    Monday, July 7 2014 5:15 PM EDT2014-07-07 21:15:09 GMT
    In the past ten years, the number of total knee replacements in the U.S. has doubled and many of those patients are much younger than ever before. Now, new technology allows doctors to make replacement knees that are the perfect fit.more>>
    In the past ten years, the number of total knee replacements in the U.S. has doubled and many of those patients are much younger than ever before. Now, new technology allows doctors to make replacement knees that are the perfect fit.more>>
  • Breath of Life for Heart Patients

    Breath of Life for Heart Patients

    Thursday, July 3 2014 6:20 PM EDT2014-07-03 22:20:13 GMT
    Heart failure, 5.7 million people in the U.S. have it and 55-thousand die from it each year. By definition, it means your heart cannot pump enough blood and oxygen to support all your other organs. Now, a simple breath test could make it easier and faster for doctors to diagnose.more>>
    Heart failure, 5.7 million people in the U.S. have it and 55-thousand die from it each year. By definition, it means your heart cannot pump enough blood and oxygen to support all your other organs. Now, a simple breath test could make it easier and faster for doctors to diagnose.more>>
*DISCLAIMER*: The information contained in or provided through this site section is intended for general consumer understanding and education only and is not intended to be and is not a substitute for professional advice. Use of this site section and any information contained on or provided through this site section is at your own risk and any information contained on or provided through this site section is provided on an "as is" basis without any representations or warranties.
Powered by WorldNow
Powered by WorldNow
All content © Copyright 2000 - 2014 NewsChannel 5 (WTVF-TV) and WorldNow. All Rights Reserved.
For more information on this site, please read our Privacy Policy and Terms of Service.