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This drug is 20 times stronger than fentanyl and it's killing people in Tennessee

Vanderbilt doctors warn this 75-year-old drug that resurfaced in 2018 represents a major public health emergency as its true prevalence remains unknown across Tennessee communities.
Nitazenes found in Tn
Drug 20× stronger than fentanyl is causing deaths in Tennessee
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NASHVILLE, Tenn. (WTVF) — A powerful synthetic opioid that's hundreds to thousands of times more potent than morphine is emerging as a new public health threat in Tennessee, where it's been linked to more than 90 deaths.

Nitazenes, a group of synthetic opioids, can be up to 20 times more potent than fentanyl. These drugs are increasingly appearing on Tennessee streets, according to medical experts.

"This is a public health emergency. It's not just about a drug. It's really something that we need everybody to be on the same page about. We need law enforcement. We need medical doctors. We need first responders," Dr. Shravani Durbhakula said.

Durbhakula is the director of comprehensive pain services at Vanderbilt Medical Center.

"So we're talking hundreds to thousands of times more potent than morphine. And even up to 20 times more potent than fentanyl," she said. "There are very few people who are going out trying to get nitazene specifically but it happens to be mixed into these substances that they're actually going out there for."

A pharmaceutical company originally created nitazenes 75 years ago but shelved the drug because it was so potent and deadly, Durbhakula said.

"And back in 2018, we saw it resurface," Durbhakula said. "Most of it, from my understanding, is coming in from China and other places."

The drug presents unique challenges for medical professionals and first responders. Nitazenes may require multiple doses of naloxone to counteract an overdose, and many standard drug screenings don't test for the substance.

Here is where the drug can be searched for information from the CDC.

Here are more findings in Tennessee about the drug from the CDC.

"And so it's one of those things where when we don't have urine drug screens that detect this and we don't know what a patient has taken, it could lead to misdiagnosis," Durbhakula said.

The Metro Health Department said they haven't heard much about nitazenes. According to a medical examiner's report, nitazenes don't appear among the top 11 drugs found in suspected overdoses.

"We don't even know the real prevalence of what's going on," Durbhakula said.

Vanderbilt Medical Center is working to raise awareness about the drug, monitor its presence and make testing more accessible.

Have you or someone you know been affected by the opioid crisis? Watch our full story on nitazenes and share your story with reporter Kim Rafferty at kim.rafferty@NewsChannel5.com. Your experience could help save lives and inform our ongoing coverage of this public health emergency.

In this article, we used artificial intelligence to help us convert a video news report originally written by Kim Rafferty. When using this tool, both Kim and the NewsChannel 5 editorial team verified all the facts in the article to make sure it is fair and accurate before we published it. We care about your trust in us and where you get your news, and using this tool allows us to convert our news coverage into different formats so we can quickly reach you where you like to consume information. It also lets our journalists spend more time looking into your story ideas, listening to you and digging into the stories that matter.

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