As people take off for holiday destinations, it's hard not to think about U.S. COVID numbers taking off with them.
In 2020, the worst U.S. surge happened right after Thanksgiving. So what will this year bring both with more travel, but also the protection of vaccines?
Earlier this year, the University of Minnesota's Dr. Michael Osterholm said the worst wasn’t likely behind us.
"I think this is just leaving us right now with again, you know, when the virus does what it does, why does it do it? And how much can we control? It surely makes sense that more people are traveling, more people are indoors together, that this would enhance transmission but so based on last year's experience, I think we just have to be honest and say we don't know yet," Osterholm said.
Last year, no vaccine was available at this time. This year, there is widespread vaccine availability, including new authorization for kids five and up.
But add in pandemic-record travel, the delta variant, waning vaccine immunity and new surges in kids cases, Osterholm says it's a concern.
"The data from Europe, where we're now seeing countries with 80% vaccination rates still having substantial illness, and deaths occurring just reinforces the fact that we're gonna have to almost get all the population not most, at least of the population protected through vaccination and or through immunity from having had natural infection," he said. "And it's very likely that that protection will have to be enhanced with boosters on an ongoing basis going forward."
Last week, the Centers for Disease Control (CDC) advisory panel cleared boosters for all adults 18 and older. But they stopped short of urging them for all adults, only recommending them for people over 50.
Osterholm says they got it wrong, even publishing an op-ed in The Washington Post to that effect with Dr. Eric Topol.
"The big question will be what will it be like in six, eight months from now if you're getting a booster," he said. "But for now, we know that you can greatly reduce even the breakthrough infections with a booster dose."
New CDC data shows unvaccinated people are 14 times more likely to die from COVID-19.
Osterholm's op-ed says the U.S. ranks below the top 50 most vaccinated countries, at 59%.