Tennessee's Kevin Punter and Detrick Mostella combined for 47 points and the Volunteers held off Mississippi State 80-75 on Saturday.
It marked the first road win of the season for the Volunteers (9-8, 2-3 SEC). Mostella had a game-high 24 points while Punter had 23 points and five assists.
Mississippi State (7-9, 0-4) is off to a 0-4 start in SEC play for the first time since 1992-93.
Mississippi State was led by freshman Quinndary Weatherspoon, who made his first career start in the SEC. Weatherspoon had a career-best 23 points while Gavin Ware had 21 points and 10 rebounds for the Bulldogs.
It was Ware's fifth double-double of the season and the 17th double-double of his career. Ware has now scored in double digits in 16 straight games to open the season.