Interstate 40 was partially shut down for nearly 11 hours Saturday into Sunday in Putnam County.
A crash happened around 3:30 p.m. Saturday in the west bound lanes of the interstate in Cookeville.
Police said a tractor trailer's tire blew out sending the vehicle up an embankment before flipping over.
Authorities said the driver was taken to the hospital, but there was no word on how severe his injuries may have been.
The interstate reopened around 2 a.m. Sunday. No further details were available.