A head-on crash in Clarksville has closed Highway 374.
Authorities with the Clarksville Police Department said the wreck happened on the highway near Stokes Road around 4 p.m. Thursday near the Looking Glass Restaurant.
The roadway was completely shut down to drivers, and they were urged to seek alternate routes.
The wreck involved a minivan and a passenger car. Officials confirmed two people were taken to the hospital by ambulance with serious injuries that were not believed to be life-threatening.
Crews estimated the roadway would reopen around 5:30 p.m.